Reflect the refined/narrowed PICOT question and search strategies to guide the focused search for best relevant evidence.

Reflect the refined/narrowed PICOT question and search strategies to guide the focused search for best relevant
evidence. Be sure to include MESH and the Cochrane Database of systematic reviews. Limit to RCTs, 5 years,
English. DO NOT limit your search to “full text”. Library databases are more reliable and preferred over web-based
and point-of-care databases.