The essay is this: Explain what is meant by the term “knock out mouse”. Describe how knock out mice are made and give one example of how they can be used to give insights into human disease.

Make sure to have it well structured and well explained with atleast 6 cites.

Briefly Introduce knockout mice in cancer and use The example I chose is this one: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5371387/
Do talk about Knockout mice in the use of CRISPR as well and how that could revolutionize the gene knockout
Talk about other methods briefly and compare them and say which one would be better

Briefly talk about other methods and make sure they are well structured
Do describe how they are made and MAKE SURE you use the GIMP software too to draw the diagram and please do cite that too.