Use the “Introduction” to provide a summary of WHY p53 is important, AND describe some of the interesting questions related to p53 activity & function. b. Summarize the “Classical Model” of p53 ACTIVATION presented on pages 612-613 (text related to FIGURE 2).

. How to Prepare the REVIEW of the article “Modes of p53 Regulation”.
1. Read the scientific article. Please INCLUDE Figures 2 AND 4 to guide your review.
2. Please address the following points in your review:
a. Use the “Introduction” to provide a summary of WHY p53 is important, AND describe some of the interesting questions related to p53 activity & function.
b. Summarize the “Classical Model” of p53 ACTIVATION presented on pages 612-613 (text related to FIGURE 2).
c. Provide a very brief definition (i.e. 2-3 sentences AT MOST) of the following terms: ACETYLATION, UBUITINATION, METHYLATION, SUMOYLATION & NEDDYLATION.
d. Summarize the “Refined Model” of p53 ACTIVATION presented on pages 616-618 (text related to FIGURE 4).